Study links severe malaria to long-term cognitive deficits in children

Chandy John, MD, of Indiana University School of Medicine, reported that children who experienced cerebral malaria or severe malarial anemia show significant long-term cognitive and academic deficits, according to a study presented at the European Society of Clinical Microbiology and Infectious Diseases congress in Munich. Participants tested 4 to 15 years post-infection had adjusted mean differences in overall cognition of -0.41 and -0.31, and in math scores of -0.46 and -0.32, compared to unaffected peers. The findings highlight the need for interventions to prevent severe malaria and mitigate its long-term cognitive impacts.